Pharmatech Process Ointment Mixing Tanks: Precision Engineered for Perfect Blends

Experience precision, efficiency, and quality in every batch

Ointments, the cornerstone of topical medication, are meticulously crafted formulations designed to heal, soothe, and protect the skin. These semi-solid preparations, comprising a drug substance enveloped in a carefully selected base, offer a diverse range of therapeutic benefits. From shielding the skin against environmental aggressors to combating bacterial infections, the efficacy of an ointment hinges on the precise composition and delivery system.

Pharmatech Process, a pioneer in pharmaceutical equipment manufacturing, understands the intricate nuances of ointment production. Our state-of-the-art machinery is engineered to cater to the diverse requirements of ointment formulations, ensuring optimal product quality and consistency. Whether it’s an oleaginous base for deep moisturization, a water-in-oil emulsion for protection, or a water-soluble base for rapid absorption, our equipment empowers pharmaceutical manufacturers to create top-tier ointments that deliver exceptional results.

General Comments About Compounding Ointment Bases

Ointment loss during compounding

Up to 10% of an ointment may be lost due to adherence to vessel walls and mixer surfaces. To compensate, make an excess.

Heating ingredients

Use hot water (around 70°C) to melt ingredients. It provides good temperature control and prevents overheating. Heat the aqueous phase a few degrees higher than the oil phase before mixing. This prevents premature solidification due to faster cooling of the aqueous phase. Use the lowest possible temperature and shortest heating time to minimize water evaporation.

Streamlined Operations

Having a single supplier for most, if not all, bioprocessing equipment can simplify the purchasing process and potentially lead to better integration between different equipment units.

Melting ingredients in order

Melt ingredients starting with the highest melting point and gradually add those with lower melting points. This minimizes heat exposure and enhances the final product's stability.

Cooling the ointment

Do not cool the ointment rapidly with water or ice. This alters the consistency, making it stiffer.

Adding volatile ingredients

Add volatile ingredients (oils, flavors, drugs) when the product is warm. This ensures proper mixing while avoiding ingredient evaporation due to high temperatures.

Filling containers

Cool the ointment to a few degrees above solidification before filling tubes or jars. It should be a thick, viscous fluid. This minimizes layering within the container.

Final consistency

Most ointment bases reach their final consistency and texture several hours after compounding.

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Features

Versatile material handling: Can process a wide range of ingredients including oils, waxes, emulsions, and aqueous solutions.
Precise temperature control: Accurate heating and cooling systems for optimal ingredient melting and mixing.
Homogeneous mixing: Efficient mixing chambers and agitators to ensure uniform product consistency.
Sterile environment: Designed to maintain hygienic conditions throughout the process to prevent contamination.
PLC-based control system: Enables precise control over the entire manufacturing process.
Automated operations: Reduces manual intervention and minimizes human error.
In-line homogenization: Ensures fine particle dispersion for smooth texture.
Vacuum systems: For removing air and moisture from the product.